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KMID : 1202020090020010053
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Journal of Korean Thyroid Association
2009 Volume.2 No. 1 p.53 ~ p.61
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Rapid Progression and Death in Patients with Differentiated Thyroid Cancer after Radioiodine Therapy: Report of 4 Cases
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Kang Sung-Min
Lee Sang-Woo
Ahn Byung-Cheol
Lee Jae-Tae
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Abstract
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Radioiodine therapy of differentiated thyroid cancer patient has been widely used for the treatment of recurrent or metastatic lesions after appropriate surgery. It requires thyroid stimulating hormone (TSH) stimulation to facilitate radioiodine uptake into cancer tissue. Traditional TSH stimulation method is thyroid hormone withdrawal for certain period, but it causes overt hypothyroidism and rarely results in tumor progression. We here report four cases of abrupt aggravation of pre-exsting thyroid cancer during thyroid hormone withdrawal for preparation and eventually lead to death after radioiodine therapy.
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KEYWORD
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Differentiated thyroid cancer, Progression, Thyroid hormone withdrawal, Rdioiodine therapy
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